Clinical Trials
Brain Health & the Microbiome: A Proof-of-Concept Study in Patients with Mild Cognitive Impairment (bMicrobiome Study)
Sponsor: TMCity Foundation
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigator: Mikhail Kogan, MD
Study Coordinator: Abdelmohsen Al Qalam
Study Team: Alison Warren; Mina Farah; Michaela Karam; Katherine Rangoussis; Patrick G. Corr, EdD, MEd, AFAMEE; Karol Suchowiecki; Zan Wynia
Study Overview: This study will examine the gut microbiomes of individuals with early Alzheimer's disease, mild cognitive impairment, and healthy controls to document how microbiomes may be altered following lifestyle changes—how diet, physical activity, and other health behaviors affect the microbes in the digestive tract.
Recruitment in the DMV area only: Study Brochure
D-Via: Vitamin D Delivery via Patch versus Pill & Related Microbiome Alterations—Pilot Study
In Kind Contributions: Zymo Research
Principle Investigator: Leigh A. Frame, PhD, MHS
Study Overview: On hold
Assessing possible link between mercury toxicity and risk of breast and prostate cancers
Sponsor: BUCK Cancer Foundation
Principle Investigator: Mikhail Kogan, MD
Co-Investigator: Leigh A. Frame, PhD, MHS; Patrick G. Corr, EdD, MEd, AFAMEE
Study Overview: Foundation-supported Observational Study
Program Assessment
Evaluating the GW Foundations of Integrative Medicine Research Course: A Cohort Study of Novel Curricula for Whole-Person Care Research
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Principle Investigators: Jennifer Rioux, PhD & Patrick G. Corr, EdD, MEd, AFAMEE
Study Overview: Educational Research
Lifestyle Modification Groups to Support Well-being
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigators: Patrick G. Corr, EdD, MEd, AFAMEE; Viktoriya Karakcheyeva, MD, MS, NCC, LCPC, LCADS; Ashley Drapeau, PA-C, MPAS, MC, LAc; Lorenzo Norris, MD
Study Overview: Resiliency & Well-being Center Initiative
Integrative Medicine Pharmacy Concentration Survey
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigators: Jennifer Rioux, PhD & Patrick G. Corr, EdD, MEd, AFAMEE
Study Overview: Educational Research
Evaluating the GW Integrative Medicine Programs: Nutrition, From Learning to Implementation
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigators: Julia Doto, PhD, MS
Study Overview: Educational Research, Unfunded Mixed-methods Project
Early-Stage Investigation
Investigating the relationship between vitamin D status and physical activity
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigator: Patrick G. Corr, EdD, MEd, AFAMEE
Study Team: Alia Badawi, Stephanie Vu
Study Overview: Unfunded Secondary Data Analysis Project. Phase 1, Scoping Review.
Measuring Well-being in Healthcare
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigators: Patrick G. Corr, EdD, MEd, AFAMEE; Viktoriya Karakcheyeva, MD, MS, NCC, LCPC, LCADS; Ashley Drapeau, PA-C, MPAS, MC, LAc; Lorenzo Norris, MD
Study Overview: Resiliency & Well-being Center Initiative
Gut Microbiome Knowledge & Behavior Study
Principle Investigator: Leigh A. Frame, PhD, MHS
Co-Investigator: Brad Moore, MD, MPH, FACP, DipABLM
Study Team: Benjamin Knudsen, Sasha Narain
Study Overview: Unfunded Education Intervention. Phase 1, pilot in the General Internal Medicine Clinic.
Characterizing the Gut Microbiome of Dietary Patterns using Pooled Samples: Assessing a Novel Methodological Approach to a Complex Web of Confounders
Principle Investigator: Scott A. Jackson, PhD
Co-Investigator: Leigh A. Frame, PhD, MHS; Stephanie L. Servetas, PhD
Study Team: Paulina K. Piotrowski, PhD; Sandra M. Da Silva, PhD
Study Overview: Collaboration with NIST Microbiome
Determining the impact of inpatient diet orders during admission on patient nutrition and dietary behaviors post discharge
Principle Investigator: L. Nedda Dastmalchi, DO, MA
Co-Investigator: Leigh A. Frame, PhD, MHS
Study Overview: Phase 1, Unfunded Research Project with a Cardiology Residents and Medical Students. Phase 2, Multisite Study.